← Analyst Upside

AU · rank #3 · 2026-10-20

GRAL

NASDAQ · $5.47B (USD)

SignalHold
verdict · CAUTION

The exact numbers the algorithm saw.

Factor scores and the inputs behind this pick.
Composite score
Z-score blend of all factors below.
2.774
EPS revisions (30d)
Change in consensus EPS estimate over the past 30 days ($/share).
+$0.69
Net revisions (30d)
Number of analysts revising upward minus downward.
1
Insider signal (90d)
$0 across 0 unique buyers.
-0.193
Analyst upside
Consensus target $131.30
+7.3%
Momentum acceleration
3-month minus 12-month momentum.
+64.93%
Analyst rating
5 = Strong Buy, 1 = Strong Sell.
3.91
Gross margin TTM+49.7%
52w high$166.48
Market cap (USD)$5.47B

The AI research card

Independent qualitative review of each pick before the order is placed. On the rare day the research service is unavailable, the paper book trades on the quant ranking alone and no card appears here.

Summary

GRAIL is a healthcare diagnostics company commercializing Galleri, a multi-cancer early-detection blood test capable of identifying cancer signals across more than 50 cancer types.

Rationale

Unanimous analyst target price raises (7 in 30 days) and positive estimate revisions are validated by the favorable September 2026 FDA advisory committee vote for Galleri's PMA approval and a 44.9% quarterly earnings surprise.

Material risks

  • 1The FDA could reject or delay final PMA approval or require costly long-term clinical trials demonstrating improved survival outcomes.
  • 2Persistent negative gross profit ($12.6M gross loss in Q2) and severe quarterly EBITDA losses (-$90.3M) without broad insurance reimbursement threaten balance sheet sustainability.

AI verdict council

Each pick is reviewed independently by 3 models before any order. 1 of 3 voted to proceed.

OpenAI
Caution
Claude
Caution
Gemini
Proceed